|Application ||WB, IHC-P, IF, FC, E|
|Other Accession||Q924A5, Q8K4D3, NP_510968.2|
|Calculated MW||53076 Da|
|Antigen Region||1-30 aa|
|Other Names||Proton-coupled amino acid transporter 1, Proton/amino acid transporter 1, hPAT1, Solute carrier family 36 member 1, SLC36A1, PAT1|
|Target/Specificity||This SLC36A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SLC36A1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC36A1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent, small amino acid transporter. This gene is clustered with related family members on chromosome 5q33.1.
Dorn, M., et al. J. Biol. Chem. 284(33):22123-22132(2009)
Dorn, M., et al. FEBS Lett. 583(10):1631-1636(2009)
Metzner, L., et al. Mol. Pharm. 6(3):1006-1011(2009)
Anderson, C.M., et al. J. Physiol. (Lond.) 587 (PT 4), 731-744 (2009) :
Metzner, L., et al. Biochim. Biophys. Acta 1778(4):1042-1050(2008)
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