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SLC36A1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IF, IHC-P, E |
|---|---|
| Primary Accession | Q7Z2H8 |
| Other Accession | Q924A5, Q8K4D3, NP_510968.2 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 53076 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 206358 |
|---|---|
| Other Names | Proton-coupled amino acid transporter 1, Proton/amino acid transporter 1, hPAT1, Solute carrier family 36 member 1, SLC36A1, PAT1 |
| Target/Specificity | This SLC36A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SLC36A1. |
| Dilution | IF~~1:10~50 WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SLC36A1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC36A1 (HGNC:18761) |
|---|---|
| Function | Electrogenic proton/amino acid symporter with selectivity for small apolar L-amino acids, their D-enantiomers and selected amino acid derivatives such as 4-aminobutanoate/GABA (PubMed:12809675, PubMed:12527723, PubMed:19549785). May be involved in the efflux from the lysosomal compartment of neutral amino acids resulting from proteolysis (By similarity). May play a role in specifying sites for exocytosis in neurons (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein. Note=In neurons, colocalizes with the exocyst complex in the axonal processes {ECO:0000250|UniProtKB:Q924A5} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent, small amino acid transporter. This gene is clustered with related family members on chromosome 5q33.1.
References
Dorn, M., et al. J. Biol. Chem. 284(33):22123-22132(2009)
Dorn, M., et al. FEBS Lett. 583(10):1631-1636(2009)
Metzner, L., et al. Mol. Pharm. 6(3):1006-1011(2009)
Anderson, C.M., et al. J. Physiol. (Lond.) 587 (PT 4), 731-744 (2009) :
Metzner, L., et al. Biochim. Biophys. Acta 1778(4):1042-1050(2008)
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