|Application ||WB, E|
|Other Accession||Q63250, Q9QY14, NP_036318.1|
|Calculated MW||33234 Da|
|Antigen Region||87-114 aa|
|Other Names||Forkhead box protein E3, Forkhead-related protein FKHL12, Forkhead-related transcription factor 8, FREAC-8, FOXE3, FKHL12, FREAC8|
|Target/Specificity||This FOXE3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-114 amino acids from the Central region of human FOXE3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FOXE3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor activator.|
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Provided below are standard protocols that you may find useful for product applications.
This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens-specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia.
Reis, L.M., et al. Am. J. Med. Genet. A 152A (3), 582-590 (2010) :
Bremond-Gignac, D., et al. Mol. Vis. 16, 1705-1711 (2010) :
Ali, M., et al. Mol. Vis. 16, 1162-1168 (2010) :
Anjum, I., et al. Mol. Vis. 16, 549-555 (2010) :
Iseri, S.U., et al. Hum. Mutat. 30(10):1378-1386(2009)
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