|Application ||WB, FC, E|
|Other Accession||Q8BVI5, NP_001128245.1, NP_001001433.1, NP_003754.2|
|Calculated MW||37031 Da|
|Antigen Region||247-274 aa|
|Other Names||Syntaxin-16, Syn16, STX16|
|Target/Specificity||This STX16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-274 amino acids from the C-terminal region of human STX16.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||STX16 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.|
|Cellular Location||Golgi apparatus membrane; Single-pass type IV membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants encoding different isoforms have been found for this gene.
Song, S.J., et al. Cancer Res. 69(22):8540-8544(2009)
Ganley, I.G., et al. J. Cell Biol. 180(1):159-172(2008)
Chua, C.E., et al. Mol. Membr. Biol. 25(1):35-45(2008)
Amessou, M., et al. J. Cell. Sci. 120 (PT 8), 1457-1468 (2007) :
Linglart, A., et al. Am. J. Hum. Genet. 76(5):804-814(2005)
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