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SLC25A6 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SLC25A6 Antibody (Center) AP12188C
    SLC25A6 Antibody (Center) (Cat. #AP12188c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SLC25A6 antibody detected the SLC25A6 protein (arrow).
  • IHC-P - SLC25A6 Antibody (Center) AP12188C
    SLC25A6 Antibody (Center) (Cat. #AP12188c)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC25A6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • IF - SLC25A6 Antibody (Center) AP12188C
    Confocal immunofluorescent analysis of SLC25A6 Antibody (Center)(Cat#AP12188c) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
  • FC - SLC25A6 Antibody (Center) AP12188C
    SLC25A6 Antibody (Center) (Cat. #AP12188c) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P12236
Other Accession NP_001627.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32866 Da
Antigen Region 128-155 aa
Additional Information
Gene ID 293
Other Names ADP/ATP translocase 3, ADP, ATP carrier protein 3, ADP, ATP carrier protein, isoform T2, ANT 2, Adenine nucleotide translocator 3, ANT 3, Solute carrier family 25 member 6, ADP/ATP translocase 3, N-terminally processed, SLC25A6, ANT3
Target/Specificity This SLC25A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the Central region of human SLC25A6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSLC25A6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC25A6
Synonyms ANT3
Function Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
Cellular Location Mitochondrion inner membrane; Multi-pass membrane protein. Note=The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria.
Research Areas
Citations (0)

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This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene.


Danishuddin, M., et al. J Mol Model 16(3):535-541(2010)
Hu, Z., et al. FEBS Lett. 583(2):383-388(2009)
Yang, Z., et al. Mol. Biol. Cell 18(11):4681-4689(2007)
Tu, L.C., et al. Mol. Cell Proteomics 6(4):575-588(2007)
Jang, J.Y., et al. Cell. Immunol. 241(1):14-25(2006)

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Cat# AP12188C
(40 western blots)
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