|Application ||WB, E|
|Other Accession||Q9ESS2, NP_065688.1|
|Calculated MW||19663 Da|
|Antigen Region||18-46 aa|
|Other Names||Fibroblast growth factor 22, FGF-22, FGF22|
|Target/Specificity||This FGF22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human FGF22.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FGF22 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. [provided by RefSeq].
Moffa, A.B., et al. J. Cell. Physiol. 210(3):720-731(2007)
Zhang, X., et al. J. Biol. Chem. 281(23):15694-15700(2006)
Beer, H.D., et al. Oncogene 24(34):5269-5277(2005)
Popovici, C., et al. J. Biol. Chem. 279(38):40146-40152(2004)
Umemori, H., et al. Cell 118(2):257-270(2004)
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