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>   home   >   Products   >   Primary Antibodies   >   MOZ/MYST3 Antibody (C-term)   

MOZ/MYST3 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - MOZ/MYST3 Antibody (C-term) AP12197B
    MOZ/MYST3 Antibody (C-term) (Cat. #AP12197b) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the MOZ/MYST3 antibody detected the MOZ/MYST3 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q92794
Other Accession NP_001092882
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 225028 Da
Antigen Region 1319-1351 aa
Additional Information
Gene ID 7994
Other Names Histone acetyltransferase KAT6A, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3, MYST-3, Monocytic leukemia zinc finger protein, Runt-related transcription factor-binding protein 2, Zinc finger protein 220, KAT6A, MOZ, MYST3, RUNXBP2, ZNF220
Target/Specificity This MOZ/MYST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1319-1351 amino acids from the C-terminal region of human MOZ/MYST3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMOZ/MYST3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KAT6A
Synonyms MOZ, MYST3, RUNXBP2, ZNF220
Function Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML.
Cellular Location Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus, PML body. Note=Recruited into PML body after DNA damage
Citations (0)
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Background

Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Histone acetyltransferase which may act as a transcriptional coactivator for RUNX1 and RUNX2.

References

Paggetti, J., et al. Oncogene 29(36):5019-5031(2010)
Rokudai, S., et al. J. Biol. Chem. 284(1):237-244(2009)
Murati, A., et al. Leukemia 23(1):85-94(2009)
Ullah, M., et al. Mol. Cell. Biol. 28(22):6828-6843(2008)
Katsumoto, T., et al. Cancer Sci. 99(8):1523-1527(2008)

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$ 365.00
$ 140.00
Cat# AP12197B
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