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>   home   >   Products   >   Primary Antibodies   >   PRMT8 Antibody (C-term)   

PRMT8 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PRMT8 Antibody (C-term) AP1219b
    Western blot analysis of lysates from human brain, mouse brain tissue lysate (from left to right), using PRMT8 Antibody (C-term)(Cat. #AP1219b). AP1219b was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
  • WB - PRMT8 Antibody (C-term) AP1219b
    Western blot analysis of PRMT8 Antibody (C-term) (Cat.#AP1219b) in K562 cell line lysates (35ug/lane). PRMT8 (arrow) was detected using the purified Pab.
  • WB - PRMT8 Antibody (C-term) AP1219b
    Western blot analysis of PRMT8 (arrow) using rabbit polyclonal PRMT8 Antibody (C-term) (Cat.#AP1219b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PRMT8 gene (Lane 2) (Origene Technologies).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NR22
Other Accession Q6PAK3
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 45291 Da
Antigen Region 344-373 aa
Additional Information
Gene ID 56341
Other Names Protein arginine N-methyltransferase 8, 211-, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4, PRMT8, HRMT1L3, HRMT1L4
Target/Specificity This PRMT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human PRMT8.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRMT8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRMT8
Synonyms HRMT1L3, HRMT1L4
Function Membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA). Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS.
Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side
Tissue Location Brain-specific..
Citations (0)

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Protein arginine methylation plays a role in signal transduction, RNA processing, transcriptional regulation, and DNA repair. PRMT8, a protein arginine N-methyltransferase most closely related to PRMT1, methylates the guanidino nitrogens of arginyl residues in some proteins. This protein associates with the plasma membrane following myristoylation and exhibits a brain-specific expression pattern, making it unique within this family of enzymes.


Lee,J., J. Biol. Chem. 280 (38), 32890-32896 (2005)

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$ 295.00
$ 99.00
Cat# AP1219b
(40 western blots)
Availability: In Stock
Bulk Size
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