|Application ||WB, E|
|Other Accession||Q3V1L4, O46411, NP_036361.1|
|Calculated MW||64970 Da|
|Antigen Region||5-33 aa|
|Other Names||Cytosolic purine 5'-nucleotidase, Cytosolic 5'-nucleotidase II, NT5C2, NT5B, NT5CP, PNT5|
|Target/Specificity||This NT5C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-33 amino acids from the N-terminal region of human NT5C2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NT5C2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||NT5B, NT5CP, PNT5|
|Function||May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Purine 5-prime-nucleotidase (EC 184.108.40.206) preferentially hydrolyzes inosine 5-prime-monophosphate (IMP) and other purine nucleotides, and is allosterically activated by various compounds, including ATP. The enzyme is exclusively located in the cytoplasmic matrix of cells and may have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases.[supplied by OMIM].
Niu, W., et al. Clin. Chim. Acta 411 (19-20), 1491-1495 (2010) :
Yamauchi, T., et al. Biochem. Pharmacol. 77(12):1780-1786(2009)
Newton-Cheh, C., et al. Nat. Genet. (2009) In press :
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Jordheim, L.P., et al. Drug Metab. Dispos. 36(12):2419-2423(2008)
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