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TOE1 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - TOE1 Antibody (N-term) AP12267a
    TOE1 Antibody (N-term) (Cat. #AP12267a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TOE1 antibody detected the TOE1 protein (arrow).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q96GM8
Other Accession NP_079353.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 56548 Da
Antigen Region 90-117 aa
Additional Information
Gene ID 114034
Other Names Target of EGR1 protein 1, TOE1
Target/Specificity This TOE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-117 amino acids from the N-terminal region of human TOE1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTOE1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TOE1
Function Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing (PubMed:28092684).
Cellular Location Nucleus, nucleolus. Nucleus speckle. Note=Localizes to nuclear speckles
Tissue Location Widely expressed..
Research Areas
Citations (0)
citation

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Background

TOE1 inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1.

References

Olsen, J.V., et al. Cell 127(3):635-648(2006)
De Belle, I., et al. J. Biol. Chem. 278(16):14306-14312(2003)
Robertson, N.G., et al. Genomics 23(1):42-50(1994)

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$ 182.50
$ 70.00
Cat# AP12267a
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