|Application ||WB, E|
|Other Accession||A0A087X1G2, A0A087WXS9, P0C7X1, Q6DHY5, A0A087X179, A0A087WVF3, Q6IPX1, A6NDS4, Q8IZP1, NP_001116863.1|
|Calculated MW||62185 Da|
|Antigen Region||498-527 aa|
|Other Names||TBC1 domain family member 3F, TBC1D3F, TBC1D3E|
|Target/Specificity||This TBC1D3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-527 amino acids from the C-terminal region of human TBC1D3E.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TBC1D3E Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).|
|Cellular Location||Cell membrane; Lipid-anchor. Note=Associated with lipid rafts.|
|Tissue Location||Expressed in most tissues including pancreas, thymus and testis.|
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Provided below are standard protocols that you may find useful for product applications.
TBC1D3E acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).
Alkan, C., et al. Nat. Genet. 41(10):1061-1067(2009)
Wainszelbaum, M.J., et al. J. Biol. Chem. 283(19):13233-13242(2008)
Hodzic, D., et al. Genomics 88(6):731-736(2006)
Zody, M.C., et al. Nature 440(7087):1045-1049(2006)
Paulding, C.A., et al. Proc. Natl. Acad. Sci. U.S.A. 100(5):2507-2511(2003)
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