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POU6F2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - POU6F2 Antibody (N-term) AP12281a
    POU6F2 Antibody (N-term) (Cat. #AP12281a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the POU6F2 antibody detected the POU6F2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P78424
Other Accession NP_001159490.1, NP_009183.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 73265 Da
Antigen Region 34-61 aa
Additional Information
Gene ID 11281
Other Names POU domain, class 6, transcription factor 2, Retina-derived POU domain factor 1, RPF-1, POU6F2, RPF1
Target/Specificity This POU6F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-61 amino acids from the N-terminal region of human POU6F2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPOU6F2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name POU6F2
Synonyms RPF1
Function Probable transcription factor likely to be involved in early steps in the differentiation of amacrine and ganglion cells. Recognizes and binds to the DNA sequence 5'-ATGCAAAT-3'. Isoform 1 does not bind DNA.
Cellular Location Nucleus.
Tissue Location Expressed only within the CNS, where its expression is restricted to the medical habenulla, to a dispersed population of neurons in the dorsal hypothalamus, and to subsets of ganglion and amacrine cells in the retina
Research Areas
Citations (0)

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This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.


Anney, R., et al. Hum. Mol. Genet. 19(20):4072-4082(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Di Renzo, F., et al. J. Pediatr. Hematol. Oncol. 28(12):791-797(2006)
Perotti, D., et al. J. Pediatr. Hematol. Oncol. 27(10):521-525(2005)

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$ 295.00
$ 99.00
Cat# AP12281a
(40 western blots)
Availability: In Stock
Bulk Size
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