|Application ||WB, IHC-P, FC, E|
|Calculated MW||55914 Da|
|Antigen Region||310-338 aa|
|Other Names||Hepatic triacylglycerol lipase, HL, Hepatic lipase, Lipase member C, LIPC, HTGL|
|Target/Specificity||This LIPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-338 amino acids from the Central region of human LIPC.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LIPC Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin.|
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Provided below are standard protocols that you may find useful for product applications.
LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake.
Reynolds, R., et al. Ophthalmology 117(10):1989-1995(2010)
Jablonski, K.A., et al. Diabetes 59(10):2672-2681(2010)
Hu, M., et al. Pharmacogenet. Genomics 20(10):634-637(2010)
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Kashani Farid, M.A., et al. Lipids Health Dis 9, 96 (2010) :
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