|Application ||WB, IHC-P, E|
|Calculated MW||49716 Da|
|Antigen Region||258-287 aa|
|Other Names||Ghrelin O-acyltransferase, 231-, Membrane-bound O-acyltransferase domain-containing protein 4, O-acyltransferase domain-containing protein 4, MBOAT4, GOAT, OACT4|
|Target/Specificity||This MBOAT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-287 amino acids from the Central region of human MBOAT4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MBOAT4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mediates the octanoylation of ghrelin at 'Ser-3'. Can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
|Tissue Location||Expressed predominantly in stomach with moderate levels in pancreas and relatively low levels in most other tissues.|
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Provided below are standard protocols that you may find useful for product applications.
MBOAT4 mediates the octanoylation of ghrelin at 'Ser-3'. Can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid.
Takahashi, T., et al. J. Biochem. 146(5):675-682(2009) Gomez, R., et al. Arthritis Rheum. 60(6):1704-1709(2009) Gutierrez, J.A., et al. Proc. Natl. Acad. Sci. U.S.A. 105(17):6320-6325(2008)
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