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ACTN3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ACTN3 Antibody (Center) AP12327c
    ACTN3 Antibody (Center) (Cat. #AP12327c) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the ACTN3 antibody detected the ACTN3 protein (arrow).
  • IHC-P - ACTN3 Antibody (Center) AP12327c
    ACTN3 Antibody (Center) (Cat. #AP12327c)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ACTN3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q08043
Other Accession NP_001095.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 103241 Da
Antigen Region 409-437 aa
Additional Information
Gene ID 89
Other Names Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, F-actin cross-linking protein, ACTN3
Target/Specificity This ACTN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-437 amino acids from the Central region of human ACTN3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsACTN3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACTN3
Function F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Tissue Location Expressed only in a subset of type 2 skeletal muscle fibers.
Research Areas
Citations (0)

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Alpha-actinin is an actin-binding protein with multiple roles in different cell types. This gene expression is limited to skeletal muscle. It is localized to the Z-disc and analogous dense bodies, where it helps to anchor the myofibrillar actin filaments


Rodriguez-Romo, G., et al. Eur. J. Appl. Physiol. 110(6):1099-1106(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Berman, Y., et al. Physiology (Bethesda) 25(4):250-259(2010)
Ruiz, J.R., et al. Scand J Med Sci Sports (2010) In press :
Buxens, A., et al. Scand J Med Sci Sports (2010) In press :

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$ 295.00
$ 99.00
Cat# AP12327c
(40 western blots)
Availability: In Stock
Bulk Size
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