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SFTPC Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SFTPC Antibody (N-term) AP12333A
    All lanes : Anti-SFTPC Antibody (N-term) at 1:2000 dilution Lane 1: human lung lysates Lane 2: rat lung lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 21 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IF - SFTPC Antibody (N-term) AP12333A
    Immunofluorescent analysis of Human lung tissues, using SFTPC Antibody (N-term) (Cat. #AP12333a). AP12333a was diluted at 1:25 dilution. Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). DAPI was used to stain the cell nuclear (blue).
  • WB - SFTPC Antibody (N-term) AP12333A
    SFTPC Antibody (N-term) (Cat. #AP12333a) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SFTPC antibody detected the SFTPC protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P11686
Other Accession P15783, NP_001165881.1, NP_003009.2
Reactivity Human, Mouse, Rat
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 21053 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 6440
Other Names Pulmonary surfactant-associated protein C, SP-C, Pulmonary surfactant-associated proteolipid SPL(Val), SP5, SFTPC, SFTP2
Target/Specificity This SFTPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SFTPC.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSFTPC Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SFTP2
Function Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces.
Cellular Location Secreted, extracellular space, surface film.
Research Areas
Citations (0)

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This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.


Wambach, J.A., et al. Pediatr. Res. 68(3):216-220(2010)
Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
Thouvenin, G., et al. Arch. Dis. Child. 95(6):449-454(2010)
Crossno, P.F., et al. Chest 137(4):969-973(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)

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$ 295.00
$ 99.00
Cat# AP12333A
(40 western blots)
Availability: In Stock
Bulk Size
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