|Application ||WB, IHC-P, FC, E|
|Other Accession||Q2TV78, NP_066278.3|
|Calculated MW||80320 Da|
|Antigen Region||454-483 aa|
|Other Names||Hepatocyte growth factor-like protein, Macrophage stimulatory protein, Macrophage-stimulating protein, MSP, Hepatocyte growth factor-like protein alpha chain, Hepatocyte growth factor-like protein beta chain, MST1, D3F15S2, DNF15S2, HGFL|
|Target/Specificity||This MST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-483 amino acids from the C-terminal region of human MST1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MST1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||D3F15S2, DNF15S2, HGFL|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds.
Latiano, A., et al. Inflamm. Bowel Dis. 16(7):1108-1117(2010)
Morgan, A.R., et al. Hum. Immunol. 71(6):602-609(2010)
Qiao, M., et al. Mol. Cell 38(4):512-523(2010)
McGovern, D.P., et al. Nat. Genet. 42(4):332-337(2010)
Oh, H.J., et al. Curr. Biol. 20(5):416-422(2010)
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