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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   C109B Antibody (C-term)   

C109B Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - C109B Antibody (C-term) AP12355b
    Western blot analysis of lysates from Daudi, HL-60 cell line (from left to right), using C109B Antibody (C-term)(Cat. #AP12355b). AP12355b was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
  • WB - C109B Antibody (C-term) AP12355b
    C109B Antibody (C-term) (Cat. #AP12355b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the C109B antibody detected the C109B protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NWR8
Other Accession NP_060388.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 39082 Da
Antigen Region 291-320 aa
Additional Information
Gene ID 55013
Other Names Calcium uniporter regulatory subunit MCUb, mitochondrial, MCUb, Coiled-coil domain-containing protein 109B, CCDC109B, MCUB
Target/Specificity This C109B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-320 amino acids from the C-terminal region of human C109B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsC109B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCDC109B
Synonyms MCUB
Function Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
Cellular Location Mitochondrion inner membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)

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$ 295.00
$ 99.00
Cat# AP12355b
(40 western blots)
Availability: In Stock
Bulk Size
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