|Application ||WB, FC, E|
|Calculated MW||35941 Da|
|Antigen Region||70-98 aa|
|Other Names||Galectin-4, Gal-4, Antigen NY-CO-27, L-36 lactose-binding protein, L36LBP, Lactose-binding lectin 4, LGALS4|
|Target/Specificity||This LGALS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human LGALS4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LGALS4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions.|
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Provided below are standard protocols that you may find useful for product applications.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The expression of this gene is restricted to small intestine, colon, and rectum, and it is underexpressed in colorectal cancer.
Zimbardi, A.L., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 (PT 5), 542-545 (2010) :
Stechly, L., et al. Traffic 10(4):438-450(2009)
Tripodi, D., et al. BMC Med Genomics 2, 65 (2009) :
Oberg, C.T., et al. Bioorg. Med. Chem. Lett. 18(13):3691-3694(2008)
Ideo, H., et al. J. Biol. Chem. 282(29):21081-21089(2007)
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