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CCNL2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96S94 |
| Other Accession | NP_001034666.1, NP_112199.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 58147 Da |
| Antigen Region | 338-366 aa |
| Gene ID | 81669 |
|---|---|
| Other Names | Cyclin-L2, Paneth cell-enhanced expression protein, CCNL2 |
| Target/Specificity | This CCNL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 338-366 amino acids from the Central region of human CCNL2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CCNL2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CCNL2 |
|---|---|
| Function | Involved in pre-mRNA splicing. May induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors. |
| Cellular Location | Nucleus speckle. Nucleus, nucleoplasm |
| Tissue Location | Widely expressed. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
CCNL2 is a transcriptional regulator which participates in regulating the pre-mRNA splicing process. Also modulates the expression of critical apoptotic factor, leading to cell apoptosis.
References
Loyer, P., et al. J. Biol. Chem. 283(12):7721-7732(2008)
Herrmann, A., et al. FASEB J. 21(12):3142-3152(2007)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
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