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SPATA7 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SPATA7 Antibody (C-term) AP12419b
    SPATA7 Antibody (C-term) (Cat. #AP12419b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SPATA7 antibody detected the SPATA7 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9P0W8
Other Accession NP_060888.2, NP_001035518.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 67719 Da
Antigen Region 374-401 aa
Additional Information
Gene ID 55812
Other Names Spermatogenesis-associated protein 7, HSD-31, Spermatogenesis-associated protein HSD3, SPATA7, HSD3
Target/Specificity This SPATA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-401 amino acids from the C-terminal region of human SPATA7.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSPATA7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HSD3
Function Involved in photoreceptor cells maintenance (By similarity). It is required for recruitement and proper localization of RPGRIP1 to the photoreceptor connecting cilium (CC), as well as protein trafficking across the CC to the outer segments (By similarity).
Cellular Location Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton. Note=Localizes to the microtubule network (PubMed:25398945). In the retinal photoreceptor cell layer, localizes at the connecting cilium (By similarity) {ECO:0000250|UniProtKB:Q80VP2, ECO:0000269|PubMed:25398945}
Research Areas
Citations (0)

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This gene, originally isolated from testis, is also expressed in retina. Mutations in this gene are associated with Leber congenital amaurosis and juvenile retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.


Perrault, I., et al. Hum. Mutat. 31 (3), E1241-E1250 (2010) :
Wang, H., et al. Am. J. Hum. Genet. 84(3):380-387(2009)
Zhang, X., et al. J. Mol. Med. 81(6):380-387(2003)
Heilig, R., et al. Nature 421(6923):601-607(2003)

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Cat# AP12419b
(40 western blots)
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