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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CL052 Antibody (N-term)   

CL052 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CL052 Antibody (N-term) AP12423A
    CL052 Antibody (N-term) (Cat. #AP12423a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CL052 antibody detected the CL052 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96K30
Other Accession NP_116237.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 28619 Da
Antigen Region 44-72 aa
Additional Information
Gene ID 84934
Other Names RBPJ-interacting and tubulin-associated protein 1, RBPJ-interacting and tubulin-associated protein, RITA1, C12orf52, RITA
Target/Specificity This CL052 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-72 amino acids from the N-terminal region of human CL052.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCL052 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RITA1
Synonyms C12orf52, RITA
Function Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
Cellular Location Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Shuttles rapidly between the cytoplasm and the nucleus. The function of centrosome localization is still unclear
Research Areas
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Lamesch, P., et al. Genomics 89(3):307-315(2007)

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Cat# AP12423A
(40 western blots)
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