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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TFR2 Antibody (C-term)   

TFR2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TFR2 Antibody (C-term) AP12449b
    TFR2 Antibody (C-term) (Cat. #AP12449b) western blot analysis in NCI-H292,K562 cell line lysates (35ug/lane).This demonstrates the TFR2 antibody detected the TFR2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UP52
Other Accession NP_003218.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 88755 Da
Antigen Region 674-703 aa
Additional Information
Gene ID 7036
Other Names Transferrin receptor protein 2, TfR2, TFR2
Target/Specificity This TFR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 674-703 amino acids from the C-terminal region of human TFR2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTFR2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TFR2
Function Mediates cellular uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation.
Cellular Location Cell membrane; Single-pass type II membrane protein
Tissue Location Predominantly expressed in liver. While the alpha form is also expressed in spleen, lung, muscle, prostate and peripheral blood mononuclear cells, the beta form is expressed in all tissues tested, albeit weakly
Research Areas
Citations (0)

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This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)
Ikuta, K., et al. J. Mol. Biol. 397(2):375-384(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Volke, M., et al. PLoS ONE 4 (11), E7875 (2009) :

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Cat# AP12449b
(40 western blots)
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