|Application ||WB, E|
|Other Accession||Q4R803, NP_001013648.1|
|Calculated MW||40902 Da|
|Antigen Region||238-266 aa|
|Other Names||Protein phosphatase 1 regulatory subunit 42, Leucine-rich repeat-containing protein 67, PPP1R42, LRRC67|
|Target/Specificity||This LRRC67 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 238-266 amino acids from the C-terminal region of human LRRC67.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LRRC67 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulates phosphatase activity of protein phosphatase 1 (PP1) complexes in the testis.|
|Cellular Location||Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with alpha tubulin to the manchette of developing spermatids. Detected to nuclear rim in pachytene spermatocytes. Detected at nuclear surface, opposite the acrosome in elongating spermatids. Detected at the microtubule- organizing center (MTOC). Localized to the centrosomal region of late-stage spermatids (By similarity).|
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Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
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