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RASAL1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RASAL1 Antibody (Center) AP12460c
    RASAL1 Antibody (Center) (Cat. #AP12460c) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the RASAL1 antibody detected the RASAL1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95294
Other Accession NP_004649.2, NP_001180450.1
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 90016 Da
Antigen Region 309-337 aa
Additional Information
Gene ID 8437
Other Names RasGAP-activating-like protein 1, RASAL1, RASAL
Target/Specificity This RASAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-337 amino acids from the Central region of human RASAL1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRASAL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RASAL
Function Probable inhibitory regulator of the Ras-cyclic AMP pathway.
Tissue Location Highly expressed in thyroid and adrenal medulla, lower expression in brain, spinal cord and trachea
Research Areas
Citations (0)

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The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described


Ohta, M., et al. Gastroenterology 136(1):206-216(2009)
Jin, H., et al. Proc. Natl. Acad. Sci. U.S.A. 104(30):12353-12358(2007)
Liu, Q., et al. J. Cell Biol. 170(2):183-190(2005)
Schmitt, J.M., et al. J. Biol. Chem. 277(45):43024-43032(2002)
Allen, M., et al. Gene 218 (1-2), 17-25 (1998) :

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$ 295.00
$ 99.00
Cat# AP12460c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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