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>   home   >   Products   >   Primary Antibodies   >   MINA Antibody (N-term)   

MINA Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MINA Antibody (N-term) AP12466a
    Western blot analysis of MINA (arrow) using rabbit polyclonal MINA Antibody (N-term) (Cat. #AP12466a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MINA gene.
  • FC - MINA Antibody (N-term) AP12466a
    MINA Antibody (N-term) (Cat. #AP12466a) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IUF8
Other Accession NP_001035998.1, NP_694822.2, NP_116167.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 52800 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 84864
Other Names Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA, 11411-, 60S ribosomal protein L27a histidine hydroxylase, Histone lysine demethylase MINA, MYC-induced nuclear antigen, Mineral dust-induced gene protein, Nucleolar protein 52, Ribosomal oxygenase MINA, ROX, MINA (HGNC:19441)
Target/Specificity This MINA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MINA.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMINA Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MINA (HGNC:19441)
Function Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.
Cellular Location Nucleus. Nucleus, nucleolus
Tissue Location Expressed in liver, skeletal muscle, heart, pancreas, and placenta. Not detected in brain, lung or kidney Expressed in several lung cancer tissues, but is barely detected in the adjacent non-cancerous tissues. Also highly expressed in several esophageal squamous cell carcinoma (ESCC), and colon cancer tissues, and in various cancer cell lines
Citations (0)

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MINA is a c-Myc (MYC; MIM 190080) target gene that may play a role in cell proliferation or regulation of cell growth. (Tsuneoka et al., 2002 [PubMed 12091391]; Zhang et al., 2005 [PubMed 15897898]).


Komiya, K., et al. J. Cancer Res. Clin. Oncol. 136(3):465-473(2010)
Lu, Y., et al. Cell Cycle 8(13):2101-2109(2009)
Zhang, Q., et al. Int. J. Biol. Markers 23(2):83-88(2008)
Ishizaki, H., et al. Pathol. Int. 57(10):672-680(2007)
Teye, K., et al. Oncol. Rep. 18(4):841-848(2007)

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Cat# AP12466a
(40 western blots)
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