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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   NXN Antibody (Center)   

NXN Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NXN Antibody (Center) AP12483C
    NXN Antibody (Center) (Cat. #AP12483c) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the NXN antibody detected the NXN protein (arrow).
  • IHC-P - NXN Antibody (Center) AP12483C
    NXN Antibody (Center) (Cat. #AP12483c)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NXN Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6DKJ4
Other Accession Q6GM16, P97346, NP_071908.2
Reactivity Mouse
Predicted Xenopus
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 48392 Da
Antigen Region 221-249 aa
Additional Information
Gene ID 64359
Other Names Nucleoredoxin, NXN, NRX
Target/Specificity This NXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-249 amino acids from the Central region of human NXN.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNXN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NXN
Synonyms NRX
Function Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity).
Cellular Location Cytoplasm, cytosol. Nucleus
Research Areas
Citations (0)

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NXN functions as a redox-dependent negative regulator of the Wnt signaling pathway. May function as a transcriptional regulator. May regulate phosphatase 2A (By similarity).


Ollila, H.M., et al. Mol. Psychiatry 14(4):351-353(2009)
Funato, Y., et al. Antioxid. Redox Signal. 9(8):1035-1057(2007)
Hirota, K., et al. Biochem. Biophys. Res. Commun. 274(1):177-182(2000)
Kurooka, H., et al. Genomics 39(3):331-339(1997)

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$ 295.00
$ 99.00
Cat# AP12483C
(40 western blots)
Availability: In Stock
Bulk Size
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