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TLX1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TLX1 Antibody (Center) AP12489c
    TLX1 Antibody (Center) (Cat. #AP12489c) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the TLX1 antibody detected the TLX1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P31314
Other Accession O93366, NP_005512.1
Reactivity Mouse
Predicted Chicken
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 34365 Da
Antigen Region 163-191 aa
Additional Information
Gene ID 3195
Other Names T-cell leukemia homeobox protein 1, Homeobox protein Hox-11, Proto-oncogene TCL-3, T-cell leukemia/lymphoma protein 3, TLX1, HOX11, TCL3
Target/Specificity This TLX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the Central region of human TLX1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTLX1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TLX1
Synonyms HOX11, TCL3
Function Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.
Cellular Location Nucleus.
Research Areas
Citations (0)

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This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants.


De Keersmaecker, K., et al. Nat. Med. 16(11):1321-1327(2010)
Milech, N., et al. Leuk. Res. 34(3):358-363(2010)
Zweier-Renn, L.A., et al. Genes Chromosomes Cancer 49(2):119-131(2010)
Riz, I., et al. Mol. Cancer 9, 181 (2010) :
Dear, T.N., et al. Proc. Natl. Acad. Sci. U.S.A. 90(10):4431-4435(1993)

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$ 295.00
$ 99.00
Cat# AP12489c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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