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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GBP1 Antibody (N-term)   

GBP1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GBP1 Antibody (N-term) AP12492A
    GBP1 Antibody (N-term) (Cat. #AP12492a) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the GBP1 antibody detected the GBP1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32455
Other Accession NP_002044.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 67931 Da
Antigen Region 141-170 aa
Additional Information
Gene ID 2633
Other Names Interferon-induced guanylate-binding protein 1, GTP-binding protein 1, GBP-1, HuGBP-1, Guanine nucleotide-binding protein 1, GBP1
Target/Specificity This GBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-170 amino acids from the N-terminal region of human GBP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGBP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GBP1
Function Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.
Cellular Location Cytoplasm. Golgi apparatus membrane; Lipid- anchor; Cytoplasmic side. Secreted. Note=Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of interferon-gamma induction. Golgi membrane localization requires isoprenylation and the presence of another IFN-gamma-induced factor
Research Areas
Citations (0)

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Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3.


Vopel, T., et al. J. Mol. Biol. 400(1):63-70(2010)
Mirpuri, J., et al. J. Immunol. 184(12):7186-7195(2010)
Lipnik, K., et al. Mol. Med. 16 (5-6), 177-187 (2010) :
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
O'Doherty, C., et al. Pharmacogenomics 10(7):1177-1186(2009)

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$ 295.00
$ 99.00
Cat# AP12492A
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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