|Application ||WB, IHC-P, FC, E|
|Calculated MW||130539 Da|
|Antigen Region||767-796 aa|
|Other Names||Alpha-mannosidase 2x, Alpha-mannosidase IIx, Man IIx, Mannosidase alpha class 2A member 2, Mannosyl-oligosaccharide 1, 3-1, 6-alpha-mannosidase, MAN2A2, MANA2X|
|Target/Specificity||This MAN2A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 767-796 amino acids from the Central region of human MAN2A2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MAN2A2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.|
|Cellular Location||Golgi apparatus membrane; Single-pass type II membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
MAN2A2 catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
Lesch, K.P., et al. J Neural Transm 115(11):1573-1585(2008)
Stelzl, U., et al. Cell 122(6):957-968(2005)
Hillman, R.T., et al. Genome Biol. 5 (2), R8 (2004) :
Misago, M., et al. Proc. Natl. Acad. Sci. U.S.A. 92(25):11766-11770(1995)
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