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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GDF15 Antibody (N-term)   

GDF15 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GDF15 Antibody (N-term) AP12553a
    GDF15 Antibody (N-term) (Cat. #AP12553a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GDF15 antibody detected the GDF15 protein (arrow).
  • IHC-P - GDF15 Antibody (N-term) AP12553a
    GDF15 Antibody (N-term) (Cat. #AP12553a)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GDF15 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - GDF15 Antibody (N-term) AP12553a
    GDF15 Antibody (N-term) (Cat. #AP12553a) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99988
Other Accession NP_004855.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 34140 Da
Antigen Region 51-79 aa
Additional Information
Gene ID 9518
Other Names Growth/differentiation factor 15, GDF-15, Macrophage inhibitory cytokine 1, MIC-1, NSAID-activated gene 1 protein, NAG-1, NSAID-regulated gene 1 protein, NRG-1, Placental TGF-beta, Placental bone morphogenetic protein, Prostate differentiation factor, GDF15, MIC1, PDF, PLAB, PTGFB
Target/Specificity This GDF15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human GDF15.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGDF15 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GDF15
Cellular Location Secreted.
Tissue Location Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney
Research Areas
Citations (0)

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Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.


Anand, I.S., et al. Circulation 122(14):1387-1395(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Staff, A.C., et al. Gynecol. Oncol. 118(3):237-243(2010)
Roth, P., et al. Clin. Cancer Res. 16(15):3851-3859(2010)
Huh, S.J., et al. Am. J. Pathol. 176(6):2948-2957(2010)

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Cat# AP12553a
(40 western blots)
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