|Application ||WB, IHC-P, FC, E|
|Calculated MW||34140 Da|
|Antigen Region||51-79 aa|
|Other Names||Growth/differentiation factor 15, GDF-15, Macrophage inhibitory cytokine 1, MIC-1, NSAID-activated gene 1 protein, NAG-1, NSAID-regulated gene 1 protein, NRG-1, Placental TGF-beta, Placental bone morphogenetic protein, Prostate differentiation factor, GDF15, MIC1, PDF, PLAB, PTGFB|
|Target/Specificity||This GDF15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human GDF15.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GDF15 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||MIC1, PDF, PLAB, PTGFB|
|Tissue Location||Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.
Anand, I.S., et al. Circulation 122(14):1387-1395(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Staff, A.C., et al. Gynecol. Oncol. 118(3):237-243(2010)
Roth, P., et al. Clin. Cancer Res. 16(15):3851-3859(2010)
Huh, S.J., et al. Am. J. Pathol. 176(6):2948-2957(2010)
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