|Application ||WB, IHC-P, E|
|Other Accession||P62632, Q71V39, P62631, Q32PH8, NP_001949.1|
|Predicted||Bovine, Rabbit, Rat|
|Calculated MW||50470 Da|
|Antigen Region||366-395 aa|
|Other Names||Elongation factor 1-alpha 2, EF-1-alpha-2, Eukaryotic elongation factor 1 A-2, eEF1A-2, Statin-S1, EEF1A2, EEF1AL, STN|
|Target/Specificity||This EEF1A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-395 amino acids from the C-terminal region of human EEF1A2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||EEF1A2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.|
|Tissue Location||Brain, heart, and skeletal muscle.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Zhang, Y., et al. J. Int. Med. Res. 38(3):1042-1048(2010)
Li, Z., et al. PLoS ONE 5 (5), E10755 (2010) :
Yanaka, N., et al. Biosci. Biotechnol. Biochem. 73(12):2809-2811(2009)
Lee, M.H., et al. Ann. N. Y. Acad. Sci. 1171, 87-93 (2009) :
Soares, D.C., et al. PLoS ONE 4 (7), E6315 (2009) :
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