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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   KLRC1 Antibody (N-term)   

KLRC1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KLRC1 Antibody (N-term) AP12570a
    KLRC1 Antibody (N-term) (Cat. #AP12570a) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the KLRC1 antibody detected the KLRC1 protein (arrow).
  • IF - KLRC1 Antibody (N-term) AP12570a
    Confocal immunofluorescent analysis of KLRC1 Antibody (N-term)(Cat#AP12570a) with MDA-MB435 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P26715
Other Accession NP_998822.1, NP_002250.1, NP_015567.1, NP_998823.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 26314 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 3821
Other Names NKG2-A/NKG2-B type II integral membrane protein, CD159 antigen-like family member A, NK cell receptor A, NKG2-A/B-activating NK receptor, CD159a, KLRC1, NKG2A
Target/Specificity This KLRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KLRC1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKLRC1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLRC1
Synonyms NKG2A
Function Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
Cellular Location Membrane; Single-pass type II membrane protein
Tissue Location Natural killer cells.
Research Areas
Citations (0)

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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq].


Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)
Ma, J., et al. J. Med. Virol. 82(9):1501-1507(2010)
Harrison, R.J., et al. Clin. Exp. Immunol. 161(2):306-314(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Beziat, V., et al. PLoS ONE 5 (8), E11966 (2010) :

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$ 295.00
$ 99.00
Cat# AP12570a
(40 western blots)
Availability: In Stock
Bulk Size
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