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CARTPT Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CARTPT Antibody (N-term) AP12574A
    CARTPT Antibody (N-term) (Cat. #AP12574a) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the CARTPT antibody detected the CARTPT protein (arrow).
  • IHC-P - CARTPT Antibody (N-term) AP12574A
    CARTPT Antibody (N-term) (Cat. #AP12574a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CARTPT Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16568
Other Accession NP_004282.1
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 12829 Da
Antigen Region 26-55 aa
Additional Information
Gene ID 9607
Other Names Cocaine- and amphetamine-regulated transcript protein, CART(1-39), CART(42-89), CARTPT, CART
Target/Specificity This CARTPT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human CARTPT.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCARTPT Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CART
Function Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. It promotes neuronal development and survival in vitro.
Cellular Location Secreted.
Tissue Location Hypothalamus. Found in neurons of the ventrolateral part of the arcuate nucleus, in the external zone of the median eminence, and also found in terminals in the periventricular part of the paraventricular nucleus
Research Areas
Citations (0)

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This gene encodes a secreted protein which is processed by prohormone/proprotein convertases to produce smaller, biologically active peptides. Expression of the transcript for this gene is regulated by certain drugs such as cocaine, and the encoded protein is thought to be involved in the regulation of appetite and stress. Mutations in this gene are associated with susceptibility to obesity.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Busto, A., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry 34(6):834-836(2010)
Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Rigoli, L., et al. Acta Paediatr. 99(5):722-726(2010)
Vasseur, F., et al. J. Hum. Genet. 55(4):227-231(2010)

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Cat# AP12574A
(40 western blots)
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