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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MLPH Antibody (C-term)   

MLPH Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MLPH Antibody (C-term) AP12611B
    MLPH Antibody (C-term) (Cat. #AP12611b) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the MLPH antibody detected the MLPH protein (arrow).
  • IHC-P - MLPH Antibody (C-term) AP12611B
    MLPH Antibdy (C-term) (Cat. #AP12611b)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MLPH Antibdy (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BV36
Other Accession NP_077006.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 65949 Da
Antigen Region 541-569 aa
Additional Information
Gene ID 79083
Other Names Melanophilin, Exophilin-3, Slp homolog lacking C2 domains a, SlaC2-a, Synaptotagmin-like protein 2a, MLPH, SLAC2A
Target/Specificity This MLPH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-569 amino acids from the C-terminal region of human MLPH.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMLPH Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SLAC2A
Function Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor protein MYO5A.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.


Park, J.W., et al. J. Med. Genet. 43(7):598-608(2006)
Seabra, M.C., et al. Traffic 5(6):393-399(2004)
Fukuda, M., et al. J. Cell. Sci. 117 (PT 4), 583-591 (2004) :
Lukusa, T., et al. Genet. Couns. 15(3):293-301(2004)
Menasche, G., et al. J. Clin. Invest. 112(3):450-456(2003)

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Cat# AP12611B
(40 western blots)
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