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BPGM Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - BPGM Antibody (C-term) AP12615b
    All lanes : Anti-BPGM Antibody (C-term) at 1:2000 dilution Lane 1: MDA-MB-453 whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 30 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P07738
Other Accession Q4R6L7, NP_954655.1, NP_001715.1
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 30005 Da
Antigen Region 230-259 aa
Additional Information
Gene ID 669
Other Names Bisphosphoglycerate mutase, BPGM, 3-bisphosphoglycerate mutase, erythrocyte, 3-bisphosphoglycerate synthase, 3-diphosphoglycerate mutase, DPGM, BPG-dependent PGAM, BPGM
Target/Specificity This BPGM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-259 amino acids from the C-terminal region of human BPGM.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBPGM Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC and phosphatase (EC activities.
Tissue Location Expressed in red blood cells. Expressed in non-erythroid cells of the placenta; present in the syncytiotrophoblast layer of the placental villi at the feto- maternal interface (at protein level)
Research Areas
Citations (0)

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2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.


Lamesch, P., et al. Genomics 89(3):307-315(2007)
Wang, Y., et al. J. Biol. Chem. 281(51):39642-39648(2006)
Wang, Y., et al. J. Biol. Chem. 279(37):39132-39138(2004)
Fujita, T., et al. J. Biochem. 124(6):1237-1244(1998)
Fujita, T., et al. J. Biochem. 124(6):1237-1244(1998)

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$ 295.00
$ 99.00
Cat# AP12615b
(40 western blots)
Availability: In Stock
Bulk Size
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