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KERA Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP12617b 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP12617b-ev20 Ev20 size 100 ul In Stock $ 95.00 Add to cart
  • Specification
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KERA Antibody (C-term) - Product info

ApplicationWB
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionO60938
Other AccessionNP_008966.1
ReactivityHuman
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW40509 Da

KERA Antibody (C-term) - Additional info

Gene ID 11081
Other Names
KERA; SLRR2B; Keratocan; Keratan sulfate proteoglycan keratocan
Target/Specificity
This KERA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-257 amino acids from the C-terminal region of human KERA.
Dilution
WB~~1:100~500
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
KERA Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

KERA Antibody (C-term) - Protein Information

Name KERA
Synonyms SLRR2B
Function
May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix
Cellular Location
Secreted, extracellular space, extracellular matrix (By similarity)
Tissue Location
Cornea. Increased expression in the stroma of keratoconus corneas. Also detected in trachea, and in low levels, in intestine, skeletal muscle, ovary, lung and putamen

KERA Antibody (C-term) - Related products

AP12617b: KERA Antibody (C-term)

DC06469: Human KERA cDNA Clone

KERA Antibody (C-term) - Application data

  • KERA Antibody (C-term) (Cat. #AP12617b) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the KERA antibody detected the KERA protein (arrow).

KERA Antibody (C-term) - Research Areas

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BACKGROUND

The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2).

REFERENCES

Aldave, A.J., et al. Invest. Ophthalmol. Vis. Sci. 51(8):4006-4012(2010) Dimasi, D.P., et al. Mol. Vis. 16, 562-569 (2010) : Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) : Melrose, J., et al. Arthritis Res. Ther. 10 (4), R79 (2008) : Liskova, P., et al. Mol. Vis. 13, 1339-1347 (2007) :