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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ABCD2 Antibody (C-term)   

ABCD2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ABCD2 Antibody (C-term) AP12623b
    ABCD2 Antibody (C-term) (Cat. #AP12623b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ABCD2 antibody detected the ABCD2 protein (arrow).
  • IHC-P - ABCD2 Antibody (C-term) AP12623b
    ABCD2 Antibody (C-term) (Cat. #AP12623b)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ABCD2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - ABCD2 Antibody (C-term) AP12623b
    ABCD2 Antibody (C-term) (Cat. #AP12623b) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UBJ2
Other Accession NP_005155.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 83233 Da
Antigen Region 553-582 aa
Additional Information
Gene ID 225
Other Names ATP-binding cassette sub-family D member 2, Adrenoleukodystrophy-like 1, Adrenoleukodystrophy-related protein, hALDR, ABCD2, ALD1, ALDL1, ALDR, ALDRP
Target/Specificity This ABCD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 553-582 amino acids from the C-terminal region of human ABCD2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsABCD2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ABCD2
Function Probable transporter.
Cellular Location Peroxisome membrane; Multi-pass membrane protein
Tissue Location Predominantly expressed in brain and heart.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.


Matsukawa, T., et al. Neurogenetics (2010) In press :
Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)
Maier, E.M., et al. Biochem. Biophys. Res. Commun. 377(1):176-180(2008)
Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)
Petroni, A., et al. J. Inherit. Metab. Dis. 30 (5), 828 (2007) :

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$ 295.00
$ 99.00
Cat# AP12623b
(40 western blots)
Availability: In Stock
Bulk Size
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