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TRIP13 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IHC-P, E |
|---|---|
| Primary Accession | Q15645 |
| Other Accession | Q5XHZ9, D3K5L7, Q3UA06, NP_004228.1 |
| Reactivity | Human |
| Predicted | Mouse, Pig, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 48551 Da |
| Antigen Region | 363-392 aa |
| Gene ID | 9319 |
|---|---|
| Other Names | Pachytene checkpoint protein 2 homolog, Human papillomavirus type 16 E1 protein-binding protein, 16E1-BP, HPV16 E1 protein-binding protein, Thyroid hormone receptor interactor 13, Thyroid receptor-interacting protein 13, TR-interacting protein 13, TRIP-13, TRIP13, PCH2 |
| Target/Specificity | This TRIP13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 363-392 amino acids from the C-terminal region of human TRIP13. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TRIP13 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRIP13 |
|---|---|
| Synonyms | PCH2 |
| Function | Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher- order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity). Plays a role in mitotic spindle assembly checkpoint (SAC) activation (PubMed:28553959). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer.
References
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Kang, J.U., et al. Cancer Genet. Cytogenet. 182(1):1-11(2008)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Kim, H.J., et al. Immunol. Lett. 95(2):155-159(2004)
Suzuki, H., et al. Genome Res. 11(10):1758-1765(2001)
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