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>   home   >   Products   >   Primary Antibodies   >   MRPS12 Antibody (Center K43)   

MRPS12 Antibody (Center K43)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MRPS12 Antibody (Center K43) AP12638c
    MRPS12 Antibody (Center K43) (Cat. #AP12638c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MRPS12 antibody detected the MRPS12 protein (arrow).
  • IHC-P - MRPS12 Antibody (Center K43) AP12638c
    MRPS12 Antibody (Center K43) (Cat. #AP12638c)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MRPS12 Antibody (Center K43) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15235
Other Accession NP_203526.1, NP_066930.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 15173 Da
Antigen Region 28-59 aa
Additional Information
Gene ID 6183
Other Names 28S ribosomal protein S12, mitochondrial, MRP-S12, S12mt, MT-RPS12, MRPS12, RPMS12, RPSM12
Target/Specificity This MRPS12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from the Central region of human MRPS12.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMRPS12 Antibody (Center K43) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MRPS12
Synonyms RPMS12, RPSM12
Cellular Location Mitochondrion.
Citations (0)

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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene; all three variants encode the same protein.


Zanotto, E., et al. Biochim. Biophys. Acta 1789(5):432-442(2009)
Russo, A., et al. Biochim. Biophys. Acta 1779(12):820-829(2008)
Stelzl, U., et al. Cell 122(6):957-968(2005)
Cui, Y.P., et al. World J. Gastroenterol. 9(9):1892-1896(2003)
Zhang, Z., et al. Genomics 81(5):468-480(2003)

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$ 295.00
$ 99.00
Cat# AP12638c
(40 western blots)
Availability: In Stock
Bulk Size
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