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DPT Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DPT Antibody (N-term) AP12641a
    Western blot analysis of DPT (arrow) using rabbit polyclonal DPT Antibody (N-term) (Cat. #AP12641a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DPT gene.
  • IHC-P - DPT Antibody (N-term) AP12641a
    DPT Antibody (N-term) (Cat. #AP12641a)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DPT Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q07507
Other Accession Q9QZZ6, NP_001928.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 24005 Da
Antigen Region 45-72 aa
Additional Information
Gene ID 1805
Other Names Dermatopontin, Tyrosine-rich acidic matrix protein, TRAMP, DPT
Target/Specificity This DPT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-72 amino acids from the N-terminal region of human DPT.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDPT Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DPT
Function Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation (By similarity).
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts
Research Areas
Citations (0)

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Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix assembly. The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is postulated to modify the behavior of TGF-beta through interaction with decorin. [provided by RefSeq].


Ehret, G.B., et al. Eur. J. Hum. Genet. 17(12):1650-1657(2009)
Li, X., et al. Biochemistry Mosc. 74(9):979-985(2009)
Cheung, C.L., et al. Hum. Mol. Genet. 18(4):679-687(2009)
Pochampally, R.R., et al. J. Bone Miner. Res. 22(9):1338-1349(2007)
Lunetta, K.L., et al. BMC Med. Genet. 8 SUPPL 1, S13 (2007) :

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$ 295.00
$ 99.00
Cat# AP12641a
(40 western blots)
Availability: In Stock
Bulk Size
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