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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   CA1 Antibody (N-term)   

CA1 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CA1 Antibody (N-term) AP12645a
    Western blot analysis of CA1 (arrow) using rabbit polyclonal CA1 Antibody (N-term) (Cat. #AP12645a). HEK293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CA1 gene.
  • IHC-P - CA1 Antibody (N-term) AP12645a
    CA1 Antibody (N-term) (Cat. #AP12645a)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CA1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - CA1 Antibody (N-term) AP12645a
    CA1 Antibody (N-term) (Cat. #AP12645a) flow cytometric analysis of HEK293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P00915
Other Accession NP_001122301.1, NP_001122302.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 28870 Da
Antigen Region 60-90 aa
Additional Information
Gene ID 759
Other Names Carbonic anhydrase 1, Carbonate dehydratase I, Carbonic anhydrase B, CAB, Carbonic anhydrase I, CA-I, CA1
Target/Specificity This CA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-90 amino acids from the N-terminal region of human CA1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCA1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CA1
Function Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.


Abhary, S., et al. Mol. Vis. 15, 1179-1184 (2009) :
Gambhir, K.K., et al. Biochem. Genet. 45 (5-6), 431-439 (2007) :
Temperini, C., et al. Bioorg. Med. Chem. Lett. 17(8):2210-2215(2007)
Temperini, C., et al. Bioorg. Med. Chem. Lett. 16(19):5152-5156(2006)
Dawson, S.J., et al. J. Infect. 24(3):317-320(1992)

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$ 295.00
$ 99.00
Cat# AP12645a
(40 western blots)
Availability: In Stock
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