|Application ||WB, E|
|Other Accession||Q50H32, NP_001073945.1|
|Calculated MW||32294 Da|
|Antigen Region||83-112 aa|
|Other Names||Glutaredoxin domain-containing cysteine-rich protein 1, GRXCR1, DFNB25|
|Target/Specificity||This GRXCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-112 amino acids from the Central region of human GRXCR1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GRXCR1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in actin filament architecture in developing stereocilia of sensory cells.|
|Cellular Location||Cell projection, stereocilium. Cell projection, microvillus. Cell projection, kinocilium. Note=In the inner ear, localized to stereocilia, apical microvilli of sensory cells and kinocilia|
|Tissue Location||Expressed at low levels in adult lung, brain and duodenum with moderate levels in testis. Highly expressed in fetal cochlea.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells.
Schraders, M., et al. Am. J. Hum. Genet. 86(2):138-147(2010)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Harrington, J.J., et al. Nat. Biotechnol. 19(5):440-445(2001)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.