|Application ||WB, E|
|Calculated MW||55037 Da|
|Antigen Region||410-438 aa|
|Other Names||Tripartite motif-containing protein 10, B30-RING finger protein, RING finger protein 9, TRIM10, RFB30, RNF9|
|Target/Specificity||This TRIM10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-438 amino acids from the C-terminal region of human TRIM10.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TRIM10 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Seems to play an important role in erythropoiesis.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic bodies. Studies in mice suggest that this protein plays a role in terminal differentiation of erythroid cells. Alternate splicing of this gene generates two transcript variants encoding different isoforms.
Fellay, J., et al. PLoS Genet. 5 (12), E1000791 (2009) :
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :
Shiina, T., et al. Genetics 173(3):1555-1570(2006)
Reymond, A., et al. EMBO J. 20(9):2140-2151(2001)
Orimo, A., et al. Biochem. Biophys. Res. Commun. 276(1):45-51(2000)
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