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>   home   >   Products   >   Primary Antibodies   >   SLC9A2 Antibody (C-term)   

SLC9A2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SLC9A2 Antibody (C-term) AP12705b
    SLC9A2 Antibody (C-term) (Cat. #AP12705b) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the SLC9A2 antibody detected the SLC9A2 protein (arrow).
  • IHC-P - SLC9A2 Antibody (C-term) AP12705b
    SLC9A2 Antibody (C-term) (Cat. #AP12705b)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC9A2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9UBY0
Other Accession NP_003039.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 91520 Da
Antigen Region 754-783 aa
Additional Information
Gene ID 6549
Other Names Sodium/hydrogen exchanger 2, Na(+)/H(+) exchanger 2, NHE-2, Solute carrier family 9 member 2, SLC9A2, NHE2
Target/Specificity This SLC9A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 754-783 amino acids from the C-terminal region of human SLC9A2.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSLC9A2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC9A2
Synonyms NHE2
Function Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Expressed in skeletal muscle, colon and kidney. Lower levels in the testis, prostate, ovary, and small intestine
Citations (0)

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Background

SLC9A2 is involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption.

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Son, E.J., et al. J. Cell. Biochem. 107(5):965-972(2009)
Joly, F., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 297 (1), G116-G123 (2009) :
Musch, M.W., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 296 (2), G202-G210 (2009) :
Beltran, A.R., et al. Pflugers Arch. 455(5):799-810(2008)

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Cat# AP12705b
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(40 western blots)
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