|Application ||WB, IHC-P, E|
|Calculated MW||91520 Da|
|Antigen Region||754-783 aa|
|Other Names||Sodium/hydrogen exchanger 2, Na(+)/H(+) exchanger 2, NHE-2, Solute carrier family 9 member 2, SLC9A2, NHE2|
|Target/Specificity||This SLC9A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 754-783 amino acids from the C-terminal region of human SLC9A2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC9A2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in skeletal muscle, colon and kidney. Lower levels in the testis, prostate, ovary, and small intestine|
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Provided below are standard protocols that you may find useful for product applications.
SLC9A2 is involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Son, E.J., et al. J. Cell. Biochem. 107(5):965-972(2009)
Joly, F., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 297 (1), G116-G123 (2009) :
Musch, M.W., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 296 (2), G202-G210 (2009) :
Beltran, A.R., et al. Pflugers Arch. 455(5):799-810(2008)
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