|Application ||WB, E|
|Other Accession||P70512, O08755, NP_004489.1|
|Calculated MW||51023 Da|
|Antigen Region||356-385 aa|
|Other Names||Hepatocyte nuclear factor 6, HNF-6, One cut domain family member 1, One cut homeobox 1, ONECUT1, HNF6, HNF6A|
|Target/Specificity||This ONECUT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 356-385 amino acids from the C-terminal region of human ONECUT1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ONECUT1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription.|
|Tissue Location||Highly expressed in liver; lower expression in testis and skin|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
ONECUT1 is a transcriptional activator. It binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.
Lee, Y.S., et al. Biochem. J. 413(3):559-569(2008)
Jiang, X., et al. Oncol. Rep. 19(1):157-163(2008)
Lehner, F., et al. FASEB J. 21(7):1445-1462(2007)
Rausa, F.M. III, et al. J. Biol. Chem. 279(41):43070-43076(2004)
Thomas, H., et al. Nucleic Acids Res. 32 (19), E150 (2004) :
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.