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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   FGFRL1 Antibody (N-term)   

FGFRL1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • IHC-P - FGFRL1 Antibody (N-term) AP12726a
    FGFRL1 Antibody (N-term) (Cat. #AP12726a)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FGFRL1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • WB - FGFRL1 Antibody (N-term) AP12726a
    FGFRL1 Antibody (N-term) (Cat. #AP12726a) western blot analysis in A549,HepG2,Y79 cell line lysates (35ug/lane).This demonstrates the FGFRL1 antibody detected the FGFRL1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8N441
Other Accession Q7TQM3, Q91V87, NP_001004358.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 54537 Da
Antigen Region 131-160 aa
Additional Information
Gene ID 53834
Other Names Fibroblast growth factor receptor-like 1, FGF receptor-like protein 1, FGF homologous factor receptor, FGFR-like protein, Fibroblast growth factor receptor 5, FGFR-5, FGFRL1, FGFR5, FHFR
Target/Specificity This FGFRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-160 amino acids from the N-terminal region of human FGFRL1.
Dilution IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFGFRL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms FGFR5, FHFR
Function Has a negative effect on cell proliferation.
Cellular Location Membrane; Single-pass type I membrane protein Note=Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles
Tissue Location Expressed preferentially in cartilaginous tissues and pancreas. Highly expressed in the liver, kidney, heart, brain and skeletal muscle. Weakly expressed in the lung, small intestine and spleen.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.


Bailey, S.D., et al. Diabetes Care (2010) In press :
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
LopezJimenez, N., et al. Hum. Genet. 127(3):325-336(2010)
Steinberg, F., et al. J. Biol. Chem. 285(3):2193-2202(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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$ 295.00
$ 99.00
Cat# AP12726a
(40 western blots)
Availability: In Stock
Bulk Size
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