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ATP1B3 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP12745b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP12745b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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ATP1B3 Antibody (C-term) - Product info | |
| Application | WB, IHC
|
| Primary Accession | P54709 |
| Other Accession | NP_001670.1 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 31513 Da |
ATP1B3 Antibody (C-term) - Additional info | |
| Gene ID 483 | |
| Other Names ATP1B3; Sodium/potassium-transporting ATPase subunit beta-3; Sodium/potassium-dependent ATPase subunit beta-3; CD_antigen=CD298 | |
| Target/Specificity This ATP1B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-278 amino acids from the C-terminal region of human ATP1B3. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ATP1B3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ATP1B3 Antibody (C-term) - Protein Information | |
| Name ATP1B3 | |
| Function This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known | |
| Cellular Location Membrane; Single-pass type II membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV | |
ATP1B3 Antibody (C-term) - Related products
AP12745b: ATP1B3 Antibody (C-term)
RI10474: ATP1B3 predesign siRNA
DC03208: Human ATP1B3 cDNA Clone
ATP1B3 Antibody (C-term) - Application data
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ATP1B3 Antibody (C-term) (Cat. #AP12745b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ATP1B3 antibody detected the ATP1B3 protein (arrow).
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ATP1B3 Antibody (C-term) (Cat. #AP12745b)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ATP1B3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
ATP1B3 Antibody (C-term) - Research Areas
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BACKGROUND
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq].
REFERENCES
Floyd, R.V., et al. Reprod Sci 17(4):366-376(2010) Aughey, R.J., et al. J. Appl. Physiol. 103(1):39-47(2007) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : Chiampanichayakul, S., et al. Tissue Antigens 68(6):509-517(2006) Chi, A., et al. J. Proteome Res. 5(11):3135-3144(2006)
