|Application ||WB, IHC-P, E|
|Calculated MW||29116 Da|
|Antigen Region||100-129 aa|
|Other Names||Protein BTG3, Abundant in neuroepithelium area protein, BTG family member 3, Protein Tob5, BTG3, ANA, TOB5|
|Target/Specificity||This BTG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-129 amino acids from the Central region of human BTG3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||BTG3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Overexpression impairs serum-induced cell cycle progression from the G0/G1 to S phase.|
|Tissue Location||Ubiquitous. High expression in the ventricular zone of the developing central nervous system. High in ovary, testis, prostate, thymus and lung.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein might play a role in neurogenesis in the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
Majid, S., et al. Carcinogenesis 30(4):662-670(2009)
Yu, J., et al. Gene Expr. 14(3):173-182(2008)
Ou, Y.H., et al. EMBO J. 26(17):3968-3980(2007)
Lim, J., et al. Cell 125(4):801-814(2006)
Yoshida, Y., et al. Jpn. J. Cancer Res. 92(6):592-596(2001)
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