|Application ||WB, IHC-P, E|
|Calculated MW||29116 Da|
|Antigen Region||100-129 aa|
|Other Names||Protein BTG3, Abundant in neuroepithelium area protein, BTG family member 3, Protein Tob5, BTG3, ANA, TOB5|
|Target/Specificity||This BTG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-129 amino acids from the Central region of human BTG3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||BTG3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Overexpression impairs serum-induced cell cycle progression from the G0/G1 to S phase.|
|Tissue Location||Ubiquitous. High expression in the ventricular zone of the developing central nervous system. High in ovary, testis, prostate, thymus and lung.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein might play a role in neurogenesis in the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
Majid, S., et al. Carcinogenesis 30(4):662-670(2009)
Yu, J., et al. Gene Expr. 14(3):173-182(2008)
Ou, Y.H., et al. EMBO J. 26(17):3968-3980(2007)
Lim, J., et al. Cell 125(4):801-814(2006)
Yoshida, Y., et al. Jpn. J. Cancer Res. 92(6):592-596(2001)
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