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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   SPOPL Antibody (Center)   

SPOPL Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SPOPL Antibody (Center) AP12768c
    SPOPL Antibody (Center) (Cat. #AP12768c) western blot analysis in uterus tumor cell line lysates (35ug/lane).This demonstrates the SPOPL antibody detected the SPOPL protein (arrow).
  • IHC-P - SPOPL Antibody (Center) AP12768c
    SPOPL Antibody (Center) (Cat. #AP12768c)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SPOPL Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - SPOPL Antibody (Center) AP12768c
    SPOPL Antibody (Center) (Cat. #AP12768c) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6IQ16
Other Accession NP_001001664.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 44647 Da
Antigen Region 221-249 aa
Additional Information
Gene ID 339745
Other Names Speckle-type POZ protein-like, HIB homolog 2, Roadkill homolog 2, SPOPL
Target/Specificity This SPOPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-249 amino acids from the Central region of human SPOPL.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSPOPL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes that contain SPOP.
Cellular Location Nucleus.
Research Areas
Citations (0)

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In complex with a cullin, may act in ubiquitination and proteasomal degradation processes (By similarity).


Lamesch, P., et al. Genomics 89(3):307-315(2007)
Zhang, Q., et al. Dev. Cell 10(6):719-729(2006)
Kent, D., et al. Development 133(10):2001-2010(2006)

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$ 295.00
$ 99.00
Cat# AP12768c
(40 western blots)
Availability: In Stock
Bulk Size
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