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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   LINGO4 Antibody (C-term)   

LINGO4 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - LINGO4 Antibody (C-term) AP12795b
    Anti-LINGO4 Antibody (C-term) at 1:1000 dilution + human liver lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 64 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - LINGO4 Antibody (C-term) AP12795b
    LINGO4 Antibody (C-term) (Cat. #AP12795b) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the LINGO4 antibody detected the LINGO4 protein (arrow).
  • IHC-P - LINGO4 Antibody (C-term) AP12795b
    LINGO4 Antibody (C-term) (Cat. #AP12795b)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of LINGO4 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q6UY18
Other Accession Q149C3, NP_001004432.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 543-571 aa
Additional Information
Other Names Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4, Leucine-rich repeat neuronal protein 6D, LINGO4, LRRN6D
Target/Specificity This LINGO4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-571 amino acids from the C-terminal region of human LINGO4.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLINGO4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LINGO4
Synonyms LRRN6D
Cellular Location Membrane; Single-pass type I membrane protein EMBL; AY358115; AAQ88482.1; -; mRNA EMBL; AL589765; -; NOT_ANNOTATED_CDS; Genomic_DNA CCDS; CCDS30855.1; - RefSeq; NP_001004432.1; NM_001004432.3 UniGene; Hs.591477; - ProteinModelPortal; Q6UY18; - SMR; Q6UY18; - STRING; 9606.ENSP00000357810; - iPTMnet; Q6UY18; - PhosphoSitePlus; Q6UY18; - BioMuta; LINGO4; - DMDM; 74762377; - PaxDb; Q6UY18; - PeptideAtlas; Q6UY18; - PRIDE; Q6UY18; - ProteomicsDB; 67695; - Ensembl; ENST00000368820; ENSP00000357810; ENSG00000213171 GeneID; 339398; - KEGG; hsa:339398; - UCSC; uc001ezf.2; human CTD; 339398; - DisGeNET; 339398; - EuPathDB; HostDB:ENSG00000213171.2; - GeneCards; LINGO4; - HGNC; HGNC:31814; LINGO4 HPA; HPA060781; - MIM; 609794; gene neXtProt; NX_Q6UY18; - OpenTargets; ENSG00000213171; - PharmGKB; PA162394098; - eggNOG; KOG0619; Eukaryota eggNOG; COG4886; LUCA GeneTree; ENSGT00760000118831; - HOGENOM; HOG000246971; - HOVERGEN; HBG057546; - InParanoid; Q6UY18; - OMA; KGRVKHH; - OrthoDB; EOG091G047N; - PhylomeDB; Q6UY18; - TreeFam; TF334360; - GenomeRNAi; 339398; - PRO; PR:Q6UY18; - Proteomes; UP000005640; Chromosome 1 Bgee; ENSG00000213171; - CleanEx; HS_LINGO4; - Genevisible; Q6UY18; HS GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO; GO:0007409; P:axonogenesis; IBA:GO_Central Gene3D; 2.60.40.10; -; 1 Gene3D; 3.80.10.10; -; 1 InterPro; IPR000483; Cys-rich_flank_reg_C InterPro; IPR007110; Ig-like_dom InterPro; IPR036179; Ig-like_dom_sf InterPro; IPR013783; Ig-like_fold InterPro; IPR013098; Ig_I-set InterPro; IPR003599; Ig_sub InterPro; IPR003598; Ig_sub2 InterPro; IPR001611; Leu-rich_rpt InterPro; IPR003591; Leu-rich_rpt_typical-subtyp InterPro; IPR032675; LRR_dom_sf InterPro; IPR000372; LRRNT Pfam; PF07679; I-set; 1 Pfam; PF13855; LRR_8; 4 SMART; SM00409; IG; 1 SMART; SM00408; IGc2; 1 SMART; SM00369; LRR_TYP; 10 SMART; SM00082; LRRCT; 1 SMART; SM00013; LRRNT; 1 SUPFAM; SSF48726; SSF48726; 1 PROSITE; PS50835; IG_LIKE; 1 PROSITE; PS51450; LRR; 8 2: Evidence at transcript level; Complete proteome; Disulfide bond; Glycoprotein; Immunoglobulin domain; Leucine-rich repeat; Membrane; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix SIGNAL 1 28 CHAIN 29 593 Leucine-rich repeat and immunoglobulin- like domain-containing nogo receptor- interacting protein 4 /FTId=PRO_0000324184 TOPO_DOM 29 533 Extracellular. TRANSMEM 534 554 Helical. TOPO_DOM 555 593 Cytoplasmic. DOMAIN 29 60 LRRNT REPEAT 61 82 LRR 1 REPEAT 85 106 LRR 2 REPEAT 109 130 LRR 3 REPEAT 133 154 LRR 4 REPEAT 157 178 LRR 5 REPEAT 181 202 LRR 6 REPEAT 210 231 LRR 7 REPEAT 253 274 LRR 8 REPEAT 277 298 LRR 9 REPEAT 301 322 LRR 10 REPEAT 325 346 LRR 11 DOMAIN 358 412 LRRCT DOMAIN 412 502 Ig-like C2-type CARBOHYD 191 191 N-linked (GlcNAc...) asparagine CARBOHYD 253 253 N-linked (GlcNAc...) asparagine CARBOHYD 263 263 N-linked (GlcNAc...) asparagine CARBOHYD 492 492 N-linked (GlcNAc...) asparagine CARBOHYD 508 508 N-linked (GlcNAc...) asparagine CARBOHYD 515 515 N-linked (GlcNAc...) asparagine DISULFID 435 484 {ECO:0000255|PROSITE-ProRule:PRU00114} SEQUENCE 593 AA; 63774 MW; 47514FD64574FA71 CRC64; MDAATAPKQA WPPWPPLLFL LLLPGGSGGS CPAVCDCTSQ PQAVLCGHRQ LEAVPGGLPL DTELLDLSGN RLWGLQQGML SRLSLLQELD LSYNQLSTLE PGAFHGLQSL LTLRLQGNRL RIMGPGVFSG LSALTLLDLR LNQIVLFLDG AFGELGSLQK LEVGDNHLVF VAPGAFAGLA KLSTLTLERC NLSTVPGLAL ARLPALVALR LRELDIGRLP AGALRGLGQL KELEIHLWPS LEALDPGSLV GLNLSSLAIT RCNLSSVPFQ ALYHLSFLRV LDLSQNPISA IPARRLSPLV RLQELRLSGA CLTSIAAHAF HGLTAFHLLD VADNALQTLE ETAFPSPDKL VTLRLSGNPL TCDCRLLWLL RLRRHLDFGM SPPACAGPHH VQGKSLKEFS DILPPGHFTC KPALIRKSGP RWVIAEEGGH AVFSCSGDGD PAPTVSWMRP HGAWLGRAGR VRVLEDGTLE IRSVQLRDRG AYVCVVSNVA GNDSLRTWLE VIQVEPPNGT LSDPNITVPG IPGPFFLDSR GVAMVLAVGF LPFLTSVTLC FGLIALWSKG KGRVKHHMTF DFVAPRPSGD KNSGGNRVTA KLF
Research Areas
Citations (0)

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Background

The exact function of LINGO4 remains unknown.

References

Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)

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$ 295.00
$ 99.00
Cat# AP12795b
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(40 western blots)
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